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Editor's Correspondence
September 18, 2006

Corticosteroids in Atrial Fibrillation: Friends or Foes?

Arch Intern Med. 2006;166(16):1785. doi:10.1001/archinte.166.16.1785-a

I read with great interest the recent contribution by van der Hooft et al,1 which provided epidemiological evidence for an association between high-dose corticosteroid exposure (oral or parenteral steroid at a daily dose of ≥7.5 mg of prednisone equivalents) and the development of AF. A direct arrhythmogenic effect of these agents was also speculated, and some potential triggering mechanisms were proposed.1

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