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Editor's Correspondence
April 23, 2007

Community-Associated Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections in Men Who Have Sex With Men in New York City

Arch Intern Med. 2007;167(8):854-857. doi:10.1001/archinte.167.8.854

Methicillin-resistant Staphylococcus aureus (MRSA) was once considered to be an exclusively nosocomial pathogen. However, in the late 1990s, community-associated MRSA (CA-MRSA) was first reported in otherwise healthy children and has since emerged as a significant pathogen outside the hospital setting.1,2 Outbreaks have been described in several populations, including athletes, military recruits, prisoners, and men who have sex with men (MSM), as well as in certain ethnic groups, including Native Americans and Pacific Islanders.312 This organism has been most often associated with skin and soft tissue infections.1318 Prior studies have shown that CA-MRSA isolates are susceptible to trimethoprim-sulfamethoxazole combination, clindamycin, fluoroquinolones, tetracyclines, rifampin, vancomycin, and linezolid.6,10,15,1721 However, the susceptibility patterns have varied among geographic areas.10,15,1719 In our urban community, we have observed a high incidence of CA-MRSA skin and soft tissue infections in the MSM population as well as frequent recurrences. To date, recurrence rates have not been well described in the literature. We sought to characterize CA-MRSA skin and soft tissue infections in the MSM population in our community.

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