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Editor's Correspondence
October 8, 2007

High-Sensitivity C-Reactive Protein and Prediction of Nontraumatic Fractures—Reply

Arch Intern Med. 2007;167(18):2007-2008. doi:10.1001/archinte.167.18.2007-c

In reply

The primary aim of our study was to test whether low-grade systemic inflammation as estimated by hs-CRP level is linked to the risk of nontraumatic fractures.1 The hypothesis that inflammation interferes with bone metabolism and affects fracture risk is intriguing from a pathophysiologic and therapeutic viewpoint. Our and other recent epidemiological data1,2 support this view and intend to stimulate further research efforts in the field.

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