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Editor's Correspondence
March 10, 2008

Low-Dose Rosiglitazone in Patients With Type 2 Diabetes Mellitus Requiring Insulin Therapy

Arch Intern Med. 2008;168(5):548. doi:10.1001/archinte.168.5.548

We would like to raise the following issues regarding the interesting article by Hollander et al.1 The high dropout rates (176 of the 630 randomized subjects) reported in the study may have reduced power and comparability and thus limit the validity of the results.2 Furthermore, including sample size estimation in the manuscript would facilitate assessment of the impact of follow-up losses on the study results.

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