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December 14, 2009

Errors in Text in: APOE Genotype, Lipids, and Coronary Heart Disease Risk: A Prospective Population Study

Author Affiliations

Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2009

Arch Intern Med. 2009;169(22):2108. doi:10.1001/archinternmed.2009.429

Errors in Text. In the Original Investigation titled “APOE Genotype, Lipids, and Coronary Heart Disease Risk: A Prospective Population Study” by Ward et al, published in the August 10/24 issue of the Archives (2009;169[15]:1424-1429), errors occurred in the last paragraph of the “Introduction” on page 1425. The third sentence should have read, “Within this cohort, it was previously observed that the LDL-C level was relatively lower among *E2 carriers and higher among *E4 carriers8; however, the association between APOE and CHD risk within the EPIC-Norfolk cohort was not characterized in previous analyses.” An error also occurred in the first paragraph of the “Comment” section on pages 1426 and 1427. The first sentence should have read, “The respective lower and marginally higher CHD risk observed among the *E2+ and *E4+ groups in the age- and sex-adjusted analyses of the EPIC-Norfolk cohort is similar to the results obtained in the recent meta-analysis of 17 studies, in which the odds ratios were 0.80 (95% CI, 0.70-0.90) for *E2 carriers and 1.06 (0.99-1.13) for *E4 carriers relative to the *E3 homozygous group.7

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