The problem of treatment-emergent hyperglycemia or DM in adolescent or adult patients treated with atypical APDs has become a major concern for psychiatrists.1- 3 In their study, Lipscombe et al4 extend the scope to elderly patients (mean age, 78 years) with preexistent DM. Their data convincingly show an increased risk for hyperglycemia in different groups of diabetic patients with APDs, thereby adding another risk factor to the use of APDs in this population.
De Hert MA, Cohen D. Antipsychotic Use and Risk for Hyperglycemia in Elderly Patients With DM. Arch Intern Med. 2009;169(22):2162-2166. doi:10.1001/archinternmed.2009.449