November 28, 2005

When Is a New Prediction Marker Useful?A Consideration of Lipoprotein-Associated Phospholipase A2 and C-Reactive Protein for Stroke Risk

Author Affiliations

Copyright 2005 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2005

Arch Intern Med. 2005;165(21):2454-2456. doi:10.1001/archinte.165.21.2454

Ischemic stroke is a common and often devastating condition that can cause significant disability or death. In light of the dire consequences of a completed stroke, the search for improved predictive models and new markers to identify patients at heightened risk is well justified. Such high-risk patients would be candidates for proven stroke-prevention therapies including aspirin,1 antihypertensive medications, and HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitors.2

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