We appreciate the supportive comments from Walton and colleagues. Their previous empirical work helped define the scale and scope of off-label prescribing and is an important adjunct to any conceptual framework.1 We agree with their conclusion that promotional efforts may be an additional flag for clinicians and professional societies to scrutinize the evidence underlying prescribing decisions.
Largent EA, Miller FG, Pearson SD. The Pharmacist's Role in Off-label Prescribing—Reply. Arch Intern Med. 2010;170(7):658. doi:10.1001/archinternmed.2010.71