Editor's Correspondence
October 11, 2010

High or Low Doses of PPIs for Patients With Peptic Ulcer Bleeding?

Author Affiliations

Author Affiliation: Division of Gastroenterology, Department of Medicine, Changhua Christian Hospital, Changhua, Taiwan.


Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2010

Arch Intern Med. 2010;170(18):1699-1700. doi:10.1001/archinternmed.2010.353

I read with interest the article by Wang et al1 titled “High-Dose vs Non–High-Dose Proton Pump Inhibitors After Endoscopic Treatment in Patients With Bleeding Peptic Ulcer.” The authors analyzed 1157 patients from 7 randomized studies and found that non–high-dose and high-dose PPI groups had similar rebleeding episodes, surgical intervention, and mortality rates after endoscopic therapy.

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