Copyright 2010 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2010
I read with interest the article by Wang et al1 titled “High-Dose vs Non–High-Dose Proton Pump Inhibitors After Endoscopic Treatment in Patients With Bleeding Peptic Ulcer.” The authors analyzed 1157 patients from 7 randomized studies and found that non–high-dose and high-dose PPI groups had similar rebleeding episodes, surgical intervention, and mortality rates after endoscopic therapy.
Lin H. High or Low Doses of PPIs for Patients With Peptic Ulcer Bleeding?. Arch Intern Med. 2010;170(18):1699-1700. doi:10.1001/archinternmed.2010.353