As a Course Director for Advance Cardiac Life Support (ACLS) classes, I read with interest the meta-analysis by Aung and Htay1(p23) regarding vasopressin in the treatment of cardiac arrest. They conclude that although vasopressin “may be at least equivalent to epinephrine,”1(p23) guidelines “should not recommend vasopressin in resuscitation protocols.”1(p17) Their primary objection to the use of vasopressin appears to be one of cost.
Buff DD. Vasopressin Has Cost and Administration Advantages Over Epinephrine in Cardiac Arrest. Arch Intern Med. 2005;165(14):1663. doi:10.1001/archinte.165.14.1663-a