We read with great interest the recent article by Fairfield and colleagues.1 We agree with their conclusions that appropriate investigations are necessary to establish with confidence the benefit or risk associated with the use of complementary and alternative medicine by persons infected with the human immunodeficiency virus (HIV). However, our experience is that the investigation of unconventional therapies is regarded as trivial by most researchers and, consequently, high-quality scientific evidence that clearly establishes the effectiveness (or lack thereof) of these interventions is lacking.
Famularo G, De Simone C, Cifone G. Carnitine Stands on Its Own in HIV Infection Treatment. Arch Intern Med. 1999;159(10):1143-1144. doi: