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Editor's Correspondence
July 12, 1999

Is the Prevalence of Gallstones in Cirrhosis Not Higher?

Arch Intern Med. 1999;159(13):1499. doi:

In reply

In our article1 we evaluated the prevalence and incidence of gallstones in a large series of patients with cirrhosis recruited from a defined area of northern-central Italy where the inhabitants have a comparable quality of life, dietary habits, and cultural background. Corresponding data from the general population were derived from 2 large epidemiological studies done in the same geographical area as our own2 and in central Italy,3 respectively. In these series the prevalence of gallstones was 20.8% and 20.0% in women and 9.40% and 10.0% in men, respectively, thus indicating a homogeneity in the prevalence of gallstones in Italy, whereas the incidence (percentage per year) ranged from 0.47 to 0.68 independent of sex. In addition, in a series of 1450 patients attending our tertiary referring gastrointestinal centers for nonulcerative dyspepsia or irritable bowel syndrome (unpublished data, June 1997 to June 1998), the overall frequency of gallstones resulted 21.2 %(182 of 884) in women and 11.0% (62 of 566) in men.

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