I would like to acknowledge the important meta-analysis presented by Girolami et al1 on the treatment of intermittent claudication in a recent issue of the ARCHIVES. This meta-analysis provides an up-to-date evaluation of the current therapies for claudication, including physical training, smoking cessation, and drug therapies. Their literature search seems to be accurate and comprehensive. However, their conclusions are rather weak and suggest that medical therapies for claudication are not all that effective.
Hiatt WR. Intermittent Claudication Revisited: The Value of Medical Therapy. Arch Intern Med. 1999;159(16):1954. doi: