Editor's Correspondence
October 25, 1999

Influence of Coinfection With Hepatitis Viruses on Human Immunodeficiency Plasma Viral Load

Author Affiliations

Copyright 1999 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1999

Arch Intern Med. 1999;159(19):2367-2368. doi:

About 40% of patients infected with human immunodeficiency virus (HIV) are coinfected with hepatitis C virus (HCV), mainly because both viruses share the same routes of transmission. It has been demonstrated by several studies that HIV infection causes a more rapid progression of chronic hepatitis C to cirrhosis and liver failure.1,2 In agreement with that, increased degrees of hepatitis C viremia have been observed in coinfected patients.1,3 Among the mechanisms potentially implicated, interaction between the viruses and the immunosuppressive state induced by HIV infection have been suggested.3,4

First Page Preview View Large
First page PDF preview
First page PDF preview