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Editor's Correspondence
November 8, 1999

Neurocardiogenic Syncope and Cancer: A Paraneoplastic Association?

Arch Intern Med. 1999;159(20):2484. doi:

I read with interest the article by Vloka et al1 that was recently published in the ARCHIVES. I would like to add to their interesting correlations between neurocardiogenic syndrome and other conditions; we recently reported2 the same syndrome accompanied by Prinzmetal angina and bronchogenic carcinoma. At the time of that report, we saw a patient with severe, recent-onset, crescendo, life-threatening manifestations of neurogenic imbalance that were totally and immediately relieved by administration of a chemotherapeutic agent. At 2-year follow-up, this patient is clinically free of disease (carcinoma) and totally asymptomatic for syncope, angina, and arrhythmias and is not receiving any medication.

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