We found the review by de Valk and Marx1 on iron, atherosclerosis, and ischemic heart disease extremely interesting. The primary reason for our interest concerns the situation of dietary iron overload in many populations in southern Africa, a phenomenon that is associated, inter alia, with a low frequency of severe atherosclerosis and/or a low occurrence of ischemic heart disease (IHD).
Walker ARP, Walker BF. Iron and Ischemic Heart Disease in the African Setting. Arch Intern Med. 2000;160(2):241. doi: