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Editor's Correspondence
January 24, 2000

Treatment of Human Immunodeficiency Virus Enteropathy With a Gluten-Free Diet

Arch Intern Med. 2000;160(2):244. doi:

Chronic diarrhea is a frequent complaint in patients with acquired immunodeficiency syndrome (AIDS). In most cases, the cause of diarrhea remains unexplained after extensive evaluation. The presence of intestinal injury and dysfunction in the absence of pathogens was an early observation in patients with AIDS,1 and the name human immunodeficiency virus (HIV) enteropathy was introduced in an attempt to group such patients into a single entity. Structural and functional findings in patients with HIV enteropathy are similar to those found in patients with celiac disease. In such patients, diarrhea usually resolves after treatment with a gluten-free diet.2,3 The purpose of this article was to investigate the effect of a gluten-free diet in patients with HIV enteropathy.

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