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Editor's Correspondence
April 24, 2000

Prostate Cancer Screening in High-Risk Patients

Author Affiliations

Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000

Arch Intern Med. 2000;160(8):1204. doi:

Many forms of cancer, such as prostate, breast, and colon cancer, can run in families. Patients with afflicted relatives often request screening, and they look to us for guidance.

A 72-year-old white man whose father died from prostate cancer had the following prostate-specific antigen (PSA) values: 1.2 ng/mL in December 1996, 1.4 ng/mL in July 1997, 1.6 ng/mL in May 1998, 1.6 ng/mL in October 1998, and 1.9 ng/mL in March 1999. At the patient's request, because of the rise in PSA levels, urological consultation was obtained, and adenocarcinoma of the prostate (Gleason score, 6) was subsequently diagnosed.

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