We thank Čáp and Ryška for their kind interest in our article.1 As we outlined previously, the available evidence on the risk of thyroid carcinoma for patients with Graves disease is almost exclusively based on pathological studies performed on surgical specimens obtained from patients with Graves disease who have undergone thyroidectomy. The results reported by Čáp and Ryška from the pathological examination of a wide number of patients with Graves disease who underwent thyroidectomy contribute additional data to support the results of previous surgical series.
Cantalamessa L, Baldini M, Orsatti A, Meroni L, Amodei V, Castagnone D. Thyroid Nodules and Carcinoma in Graves Disease—Reply. Arch Intern Med. 2000;160(10):1537-1538. doi: