Rice1 indicates that "a patient presenting with blood changes indicative of megaloblastic anemia, a low B12 level, and no history of veganism or gastrointestinal disease could realistically have nothing other than pernicious anemia." He suggests that "the results of antibody tests would add little information to the diagnosis" and that the Schilling test is not important in the management of macrocytic anemia. We disagree with these assertions.
Andrès E, Goichot B, Schlienger J. Food Cobalamin Malabsorption: A Usual Cause of Vitamin B12 Deficiency. Arch Intern Med. 2000;160(13):2061-2067. doi: