The recent study by Greenberg and Cello1 reached negative conclusions regarding the opportunity to eradicate Helicobacter pylori in patients with nonulcer dyspepsia. The authors found that, at 1 year, the change in dyspeptic symptoms was the same in the group receiving an eradicating treatment as in the placebo group. Furthermore, patients with persistent H pylori infection showed a greater, but not significant, improvement in symptoms than those with successful eradication during the follow-up.
Cammarota G, Cianci R, Gasbarrini G. Nonulcer Dyspepsia and Helicobacter pylori Infection. Arch Intern Med. 2000;160(14):2225. doi: