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Editor's Correspondence
September 11, 2000

Hyperforin in Extracts of St John's Wort (Hypericum perforatum) for Depression

Arch Intern Med. 2000;160(16):2546. doi:

We read with interest the article of Gaster and Holroyd1 on St John's wort for depression. However, the authors do not mention the substance hyperforin as a component of Hypericum extracts. Hyperforin was first mentioned,2,3 and again recently discussed,4,5 as an antibiotic.

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