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Editor's Correspondence
October 23, 2000

β-Blockers in Congestive Heart Failure: Is There a Difference Between Classes?

Author Affiliations

Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000

Arch Intern Med. 2000;160(19):3005-3006. doi:

I read with great interest the article by Bonet et al1 regarding the benefits of vasodilating and nonvasodilating agents. Clearly, it would be useful clinically to know if vasodilating β-blockers such as carvedilol are more effective than less expensive, nonvasodilating β-blockers such as metoprolol.

The authors draw the conclusion that vasodilating β-blockers had a greater effect on overall mortality than nonvasodilating β-blockers. That conclusion is a matter of statistical interpretation and not wholly supported by the authors.

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