Long-term anticoagulation therapy is important in the management of patients with chronic atrial fibrillation,1,2 deep vein thrombosis,3 prosthetic heart valves,4 and some cases of post–myocardial infarction5 because it reduces the incidence of thromboembolic complications and prolongs life.1,2,5 However, thromboembolism may still occur and, more frequently, hemorrhage may develop as a complication. Indeed, it was not until several trials showed that its advantages outweighed its disadvantages1,2,4,6 that anticoagulation therapy gained widespread acceptance.
Kajubi SK. Additional Monitoring Tools to Improve the Quality of Anticoagulation Management. Arch Intern Med. 2000;160(19):3006. doi: