We found the article by Vuksan et al1 recently published in the ARCHIVES most interesting and valuable. The data illustrate beautifully the hazards of the various "natural" herbal remedies so widely used these days. Although the ginseng and placebo preparations used in all 19 subjects were from a single manufacturer's lot, there was marked variation in glycemic effect. The number of subjects was too small to estimate confidence limits.
Ritter G, Dembicki EL. The Variable Effects of Whole-Leaf Digitalis Is a Paradigm of the Glycemic Effects of Ginseng. Arch Intern Med. 2000;160(21):3330-3331. doi: