[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.163.92.62. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
October 1919

PROTOZOOLOGIC AND CLINICAL STUDIES ON THE TREATMENT OF PROTOZOAL DYSENTERY WITH BENZYL BENZOATEI. A PRELIMINARY REPORT ON EIGHT CASES OF ENDAMEBIC DYSENTERY AND ONE CASE OF BACILLARY DYSENTERY TREATED AT THE PHILIPPINE GENERAL HOSPITAL

Author Affiliations

MANILA, P. I. WITH AN ADDENDUM BY M. A. ASUZANO, M.D. BAGUIO, P. I.

Arch Intern Med (Chic). 1919;24(4):383-397. doi:10.1001/archinte.1919.00090270029003
Abstract

Several months ago the attention of the senior author was attracted by the investigation of the action of the benzyl esters carried out by Macht1 at Johns Hopkins University. The pharmacologic action of the two esters, benzyl acetate and benzyl benzoate, which formed the subject of Macht's investigations, suggested, as Macht has pointed out, their application to the treatment of the protozoal dysenteries, especially in view of the nontoxic nature of these infections. In his paper, Macht cited a case in which benzyl benzoate was applied, with apparent success, in the treatment of a case of endamebiasis of fifteen years' standing which had been contracted in the Philippine Islands, and this determined us to make a trial of the drug in the wards of the Philippine General Hospital.

Some benzyl benzoate was prepared locally for us and it was found to exert no untoward effects on guinea-pigs when injected pure

First Page Preview View Large
First page PDF preview
First page PDF preview
×