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December 1920


Author Affiliations


From the Medical Clinic and the Nelson Morris Memorial Institute for Medical Research of the Michael Reese Hospital.

Arch Intern Med (Chic). 1920;26(6):759-767. doi:10.1001/archinte.1920.00100060114007

II Uniformity of methods of procedure of the test for hyperglycemia after glucose ingestion has resulted in rather uniform conclusions regarding the test. Hopkins,1 Hamman and Hirschman,2 Janney and Isaacson,3 Williams and Humphreys4 showed that the normal individual usually reacted to a given dosage of glucose by a maximum rise in one-half hour and almost immediate drop after the half hour. The maximum rise rarely exceeded 0.16. Bailey5 reports a normal alimentary glucose test in which the blood sugar in the whole blood was 0.172 in thirty-five minutes, 0.22 in one hour, and 0.216 in one hour and twenty-five minutes after the ingestion of 75 gm. of glucose. This type of curve is considered by most authors as distinctly abnormal, both in regard to the height which it reached and to the length of time it took before returning to normal. The diabetic curve is characterized by a rise at

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