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March 1921


Author Affiliations


From the Department of Bacteriology and Experimental Pathology, Stanford University.

Arch Intern Med (Chic). 1921;27(3):265-304. doi:10.1001/archinte.1921.00100090002001

Medical research during the past ten years has greatly advanced our knowledge of Clostridium botulinum (Bacillus botulinus) and of botulism. Recent occurences of botulism in man and domestic animals throughout the United States, and particularly in California, have drawn attention to and greatly stimulated research in all phases of this disease. Until recently these researches were conducted mainly by investigators connected with the national government and state institutions. The National Canners Association is spending large sums of money investigating food poisoning with the object of improving canning methods and preventing further outbreaks of botulism.

E. C. Dickson1 has energetically attacked the problems connected with the subject of botulism. He has established the common occurrence of botulism in the United States, the fact that toxin is found in preserved fruits and vegetables, the occurrence of two types of toxin in this country, as in Europe, the relation between C. botulinum and

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