We have recently had the opportunity to study experimentally a rather severe case of diabetes insipidus. Our observations include the effect of lumbar puncture, the administration of pituitary extract hypodermically and by mouth, the effect of histamin injection, the nitrogenous metabolism before and as affected by pituitary extract, the blood constituents and the carbohydrate tolerance.
REPORT OF CASE
J. S., male, white, aged 24 years, single, a painter and mechanic, and an overseas man, was referred to the State University of Iowa Hospital, April 25, by Dr. F. H. Lamb of Davenport, Iowa, for chronic syphilis and polyuria.
—The family history was unimportant; the patient stated, however, that one brother is a great water drinker.
—The patient complained of loss of appetite, pain in the back and lower abdomen, occasional dimness of vision, dizziness, coldness and chills, polydipsia and polyuria, general weakness, and some loss in
GIBSON RB, MARTIN FT. ADMINISTRATION OF A PITUITARY EXTRACT AND HISTAMIN IN A CASE OF DIABETES INSIPIDUS. Arch Intern Med (Chic). 1921;27(3):351-360. doi:10.1001/archinte.1921.00100090088006