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December 1921


Author Affiliations


From Brady Laboratory of Pathology and Bacteriology, Yale University School of Medicine.

Arch Intern Med (Chic). 1921;28(6):733-772. doi:10.1001/archinte.1921.00100180051005
  • Introduction.

  • General Considerations:

    1. Historical.

    2. Incidence.

    3. Clinical Characteristics.

    4. Metastases.

    5. Anatomy and Embryology.

  • Classification:

    1. According to Gross Anatomy.

    2. According to Histological Anatomy.

    3. According to Histogenesis.

  • Relation of Irritation to Neoplastic Growth.

  • Case Reports.

  • Discussion:

    1. Incidence.

    2. Clinical Characteristics.

    3. Metastases.

    4. Gross and Histologic Features.

    5. Histogenesis.

    6. Relation of Irritation to Neoplastic Growth.

  • Conclusions.

INTRODUCTION  The relative rarity of primary carcinoma of the lungs and bronchi, the difficulty of making a clinical diagnosis and the comparative inaccessibility in regard to surgical procedures, have tended to limit the practical interest in these tumors. In spite of these limitations, there is a very extensive literature on the subject which suggests, at least, a wide scientific interest in this group of neoplasms.This paper is based on the study of five cases of primary carcinoma of the lungs. The object will be to give a brief résumé of the pathology of carcinoma

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