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December 1921

OBSERVATIONS ON GLYCEMIA, GLYCURESIS, AND WATER EXCRETION IN OBESITY

Author Affiliations

ROCHESTER, MINN.

From the Section on Internal Medicine, The Mayo Clinic.

Arch Intern Med (Chic). 1921;28(6):804-812. doi:10.1001/archinte.1921.00100180122007
Abstract

Joslin1 recently emphasized the fact that many diabetics are overweight for their age, sex and height when the diagnosis of diabetes is first made, or have a history of obesity before they develop diabetic symptoms. It has seemed of interest, on this account, to observe the results of an alimentary glucose tolerance test in a series of nondiabetic obese patients in an attempt to determine how many had an abnormally low tolerance, and could, therefore, be classified on laboratory, as well as clinical evidence, as being prediabetic.

For this purpose a group of thirty-two stout persons was studied, consisting of eight men and twenty-four women who came to the Mayo clinic for obesity or for obesity and some secondary ailment which could not definitely be related to diabetes. The urine of each patient was sugar-free on routine examination.

One of the men weighed 370 pounds, one weighed 285 pounds, one

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