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November 1922


Author Affiliations


Arch Intern Med (Chic). 1922;30(5):531-547. doi:10.1001/archinte.1922.00110110002001

One hesitates in the present day to write on a subject which has been so ably and fully discussed as the Wassermann reaction,1 and to add to a literature already large. During a clinical experience of about seven years, however, in which Wassermann tests have been made as a routine measure in our medical examinations, we have had an unusual opportunity of seeing the value of the test in clinical medicine, and since our tests have been made with both sensitive and coarse (or insensitive) methods simultaneously, we have also had an opportunity to observe the value and dependability of several technics. We wish, therefore, to present briefly data and conclusions gained from more than 50,000 tests on more than 10,000 specimens of blood taken from patients the majority of whom we examined ourselves. Our Wassermann technic has been changed in some of its details from time to time. For

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