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July 1923

OBSERVATIONS ON ONE HUNDRED AND NINETY-TWO CONSECUTIVE DAYS OF THE BASAL METABOLISM, FOOD INTAKE, PULSE RATE, AND BODY WEIGHT IN A PATIENT WITH EXOPHTHALMIC GOITER

Author Affiliations

BOSTON

From the Medical Clinic of the Peter Bent Brigham Hospital, Boston.

Arch Intern Med (Chic). 1923;32(1):50-73. doi:10.1001/archinte.1923.00110190053004
Abstract

Careful studies during recent years have demonstrated, beyond question, that an elevation of the basal metabolism is a constant finding in the syndrome of exophthalmic goiter. Many careful observations have definitely established this fact and render additional and similar investigation in this direction superfluous. It seems probable, however, that further useful knowledge may be gained by the careful and intensive study of the daily metabolism of persons with exophthalmic goiter over a long period of time. By so doing our information concerning the relationship between the heightened metabolism and this disease may become more accurate and thereby extend the usefulness of basal metabolism determinations in clinical medicine. The present series of observations of the metabolism of a patient with exophthalmic goiter continued over an interval of 202 days, and the determinations were made for the purpose of securing data bearing on the following questions:

  1. The range of variation in the

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