As shown in a previous paper simple anemia is a frequent finding in cases of gastric achylia. If one were to assume that achylia is of pathogenic importance in the production of this anemia or of pernicious anemia, the question would arise why achylia should cause simple anemia in some cases and pernicious anemia in others.
Recently, evidence has been presented which suggests that pernicious anemia develops on the basis of some hereditary predisposition.
In particular Schauman1 and Martius have supported this view. A review of the known facts concerning the inheritance of pernicious anemia has recently been published by Meulengracht2. In this connection it is interesting to note that we have observed both types of anemia associated with achylia in the same family.
DIFFERENT TYPES OF ANEMIA WITH ACHYLIA IN ONE FAMILY
The following observations concern three patients with achylia of whom two, father and son, died of pernicious
FABER K, GRAM HC. THE ASSOCIATION OF ACHYLIA AND ANEMIA OF DIFFERENT TYPES IN THREE MEMBERS OF THE SAME FAMILY, AND THE BEHAVIOR OF THE COLOR INDEX IN PERNICIOUS ANEMIA. Arch Intern Med (Chic). 1924;34(6):827-832. doi:10.1001/archinte.1924.00120060094005