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This monograph is a critical and useful review of the physiology and pathology of what the author calls, the "systéme lacunaire." Under this term, the author includes: the great variety of spaces in the body, such as the intercellular spaces; the lymph spaces in the connective tissues; the subarachnoid spaces; the spaces in the internal ear containing endolymph and perilymph; the spaces in the eye containing the aqueous and vitreous humor; the serous cavities of the body, and the spaces in the joints containing synovial fluids, as well as the fluids in these varieties of spaces, and the physiology of the modification of these fluids in diseases such as edema, glaucoma, hydrocephalus and inflammations. The author points out the primitive character of this system of tissue spaces, this system antedating, both in phylogeny and autogeny, the vascular and the true lymphatic systems.
In the last chapter, the author discusses the
Apercu de la Physiologie et de la Pathologie Generales du Systeme Lacunaire.. Arch Intern Med (Chic). 1925;35(1):148. doi:10.1001/archinte.1925.00120070153013