That the subject of gastric carcinoma is a paramount one must be evident to all. About one half of all cancers occur in the stomach. Martin1 found that 0.47 per cent. of all hospital admissions are for gastric cancer. Ewing2 similarly emphasizes the great frequency of this tumor: "The stomach is probably the most frequent seat of cancer in the male, as the uterus is in the female." Whether the condition numbers one third or one half of all neoplasms is not essential, but it does demonstrate the tremendous importance of early recognition. Modern medicine and surgery avail little. Whereas our laboratory aids have advanced, our clinical intuition has lagged behind, and so we find that the diagnosis of gastric carcinoma is still terribly hopeless. Hence, any clinical means that may aid the internist or laboratory man in making an earlier diagnosis must be of distinct value.
In the study
MASTER AM. ASTHENIA AS A CHIEF COMPLAINT IN CARCINOMA OF THE STOMACH. Arch Intern Med (Chic). 1925;35(4):527-533. doi:10.1001/archinte.1925.00120100125011