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July 1925


Author Affiliations


From the Diabetic Clinic of the New England Deaconess Hospital.

Arch Intern Med (Chic). 1925;36(1):126-145. doi:10.1001/archinte.1925.00120130129012

INTRODUCTION  The use of Jerusalem artichokes, the edible vegetable in which inulin is most commonly found, in the diabetic diet has interested students of the disease ever since Külz1 and Bouchardat2 recommended it. Külz and Bouchardat believed that inulin was utilized better than starch, but von Noorden3 stated that this would not hold true with the severe cases in the same degree as with the mild ones. Sandmeyer,4 Persia,5 Lewis6 and Goudberg7 noted that inulin, when fed by mouth, appeared either not at all or in small amounts in the stools in the normal man. Sandmeyer, however, recovered in the stools more than half the inulin given to a dog, whose pancreas had been removed. Goudberg, who reviewed the subject exhaustively, gave from 100 to 200 gm. of inulin to diabetic subjects, and observed a pronounced rise in the respiratory quotient and in the metabolism, persisting for from six to

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