Tumors of the heart, although observed by the early anatomists, are of uncommon occurrence. In 1685 Zollicofferus1 wrote a dissertation on the subject, "De Polypo Cordis," and in 1700 Boneti2 noted an intracardiac polyp attached by multiple roots to the wall of the right ventricle.
There are in the literature about 150 case reports of neoplasm primary in the heart, but reviews of the subject by different writers do not agree in the number that is authentic. Eighty-six3 and thirty4 cases, respectively, were compiled in 1893, and forty-six5 and ninetyone6 in 1908. The discrepancy in these numbers is due to the question in each recorded case whether the tumor had its origin in the heart.
As indicated by the foregoing reports the most frequent of the primary tumors of the heart are fibromas, myxomas and fibromyxomas. Rhabdomyomas, lipomas, angiomas, lymphangiomas and teratomas are rare. It is maintained by several investigators
BECK CS, THATCHER HS. SPINDLE CELL SARCOMA OF THE HEART. Arch Intern Med (Chic). 1925;36(6):830-837. doi:10.1001/archinte.1925.00120180084008