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February 1926


Author Affiliations


From the medical clinics of the Johns Hopkins and the Peter Bent Brigham Hospitals.

Arch Intern Med (Chic). 1926;37(2):225-232. doi:10.1001/archinte.1926.00120200075005

The usual sequence of events following ingestion of lethal doses of mercuric chlorid has become all too familiar in the last ten years. Initially there are abdominal cramps and distress, often with bloody vomitus; diarrhea and melena may follow, and an acute tubular nephritis often supervenes with rapidly developing anuria and death in uremia in from three to twenty days. It has occasionally been noted that the course may be more rapid. Kaufmann1 cites a case of death with subnormal temperature on the second day. Zangger2 mentions the possibility of early death as do Oliver,3 Starkenstein4 and Cushny,5 and Burmeister and McNally6 have evidently observed such cases though they give no details of them. Fussell7 saw death within twelve hours; Weiss8 observed death nineteen hours after poisoning and Vaughan9 states that death may take place in thirty minutes. His description of acute collapse terminating fatally in from twelve to fourteen

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