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June 1926


Author Affiliations


From the medical clinic of the Peter Bent Brigham Hospital.

Arch Intern Med (Chic). 1926;37(6):797-814. doi:10.1001/archinte.1926.00120240069006

My object in undertaking the work discussed in this article was to evaluate the tests for biliary function that have been advocated as being of practical help to the clinician in the diagnosis or prognosis of disturbances of the biliary system.

A practical test of hepatic function must satisfy the following requirements:

  1. It must give information of a quantitative nature as to the functional capacity of any one element of the biliary system or of the biliary system as a whole.

  2. The technic of the test must be so simple that it can be carried out by any one familiar with laboratory methods.

  3. The performance of the test must require a minimal amount of time and equipment.

The liver is a complex organ and has many functions to perform. The problem of finding any one test which throws light on all the functions of the liver or which determines

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