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This is a well written and critical statement of the comparative physiology of the endocrine glands. The arrangement of the material is from the point of view of systems in the body influenced by different hormones rather than the usual descriptions of syndromes following hypoactivity or hyperactivity of the glands. The sound critical attitude of the author may be indicated by the following quotations from the initial chapter headed "Chemical Co-Ordination": "In pursuing inquiry into the endocrine or supposedly endocrine function of so-called ductless glands the physiologist has no more justification for attributing a teleological significance to every chemical entity in the organism than neo-Darwinian naturalists had for ascribing utility to every member of the body." That is to say, the author clearly recognizes that the finding of substances by various chemical treatments of organs, substances that have various physiologic actions when introduced directly into the blood or under the
The Comparative Physiology OF Internal Secretion.. Arch Intern Med (Chic). 1928;41(3):450. doi:10.1001/archinte.1928.00130150157014