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This monograph, dedicated to William N. Bullard, is not an ordinary treatise on the "disease" epilepsy, but a comprehensive analytic study of the factors involved in convulsions in general. In fact, the authors maintain that our knowledge does not permit us to designate any convulsive state as "idiopathic" or "essential" epilepsy. There is no constant anatomic lesion in epilepsy, and only a minority of patients with extensive cerebral pathologic changes have fits. The authors accept the evidence adduced in favor of vasomotor control of the cerebral vessels as conclusive and lay some stress on signs of instability of the sympathetic nervous system in epilepsy. They hail as the greatest recent advance the demonstration that changes in physiochemical processes may modify seizures profoundly. Paraphrasing the famous statement of Hippocrates that anyone who can render a man humid and dry, and hot and cold by regimen can cure epilepsy, they say: "Whoever
Medicine Monographs, Volume XIV: Epilepsy.. Arch Intern Med (Chic). 1929;43(2):295–296. doi:10.1001/archinte.1929.00130250153012