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June 1929

OPIUM ADDICTIONV. MISCELLANEOUS OBSERVATIONS ON HUMAN ADDICTS DURING THE ADMINISTRATION OF MORPHINE

Author Affiliations

PHILADELPHIA

From the Narcotic Wards of the Philadelphia General Hospital.

Arch Intern Med (Chic). 1929;43(6):878-889. doi:10.1001/archinte.1929.00130290149009
Abstract

In this paper we wish to present further results obtained from a study of a series of male opium addicts made while we were supplying their needs with morphine. These studies include fractional gastric analysis, roentgen examination of the gastro-intestinal tract, functional tests of the liver, dextrose tolerance tests, chemical and microscopic examinations of the urine, phenolsulphonphthalein tests and studies of the basal metabolic rate, temperature, blood sugar response to morphine and to epinephrine and the results of roentgen examination for persistent thymus.

FRACTIONAL GASTRIC ANALYSIS  The secretory response of free and total acid of the stomach to the standard Ewald test meal was studied by the fractional method in eighteen different addicts. In all cases, samples of gastric juice during fasting were removed for analysis. Table 1 gives the results obtained in these cases for the contents both during fasting and at intervals of fifteen minutes following completion of

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