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Article
July 1931

IS POLIOMYELITIS A DISEASE OF THE LYMPHATIC SYSTEM?

Author Affiliations

PASADENA, CALIF.

Arch Intern Med (Chic). 1931;48(1):33-50. doi:10.1001/archinte.1931.00150010038002
Abstract

It seems important to point out at this time that acute anterior poliomyelitis (infantile paralysis) may not be primarily a disease of the central nervous system, but that it may be more correctly classed with the diseases of the lymphatic systems of the body. The change that is probably common to all cases of this disease is an enlargement or a hyperplasia of some or all of the lymphatic structures of the organism. Those parts most frequently attacked are Peyer's patches and the solitary follicles of the intestines, the mesenteric lymph glands, the retroperitoneal glands, the peribronchial glands, the tonsils, the lymph glands of the neck, the axillae and the groin. In the later stages of any attack one may often make the diagnosis of the existence of the disease through noting a slight but definite enlargement of one or both of the epitrochlear glands.

While the gross enlargement of

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