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Article
February 1932

EXPERIMENTAL STUDIES ON THE EFFECT OF SECTION OF THE VAGUS NERVE ON GASTRIC SECRETION

Author Affiliations

BALTIMORE

From the Gastro-Enterological Clinic of the Department of Medicine, University of Maryland.

Arch Intern Med (Chic). 1932;49(2):234-240. doi:10.1001/archinte.1932.00150090064008
Abstract

Much interest has been manifested in recent years concerning the effect of section of the vagus nerve on the functions of the stomach. This procedure has been performed experimentally in animals and is now frequently recommended in gastric surgery in the treatment for peptic ulcer. It is commonly reported that there is a decrease in the gastric acidity after section of this nerve following subtotal gastrectomy. Considerable literature on this subject has accumulated in recent years. It may be said in general that most observers have noted a decrease in the gastric secretion following vagus section. It, however, appears from the literature that in the larger proportion of these experiments the observations have been followed only for a short period of time. What the results might have been after prolonged observations of these animals has up to the present not been clearly established.

McCrea1 investigated this subject most intensively

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