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The author begins with a condensed but fairly complete review of the factors and problems underlying water balance. He then discusses the technic of the dilution and concentration test, the results in normal persons and in patients with the various forms of renal disease and the effects of using diuretics or pituitary extract during the test. There is adequate consideration of extrarenal factors and dilution of the blood as influencing the response to water given by mouth. One gets the impression that the interpretation of a diminished or a delayed excretion of water during the dilution test is so complicated in many instances as to render the procedure valueless. The simplicity of the method is evidently no guarantee for the reliability of the results. Perhaps the most valuable feature of the "Wasserversuch" is its ability to demonstrate latent cardiac edema. After reading through this monograph, one wonders at the remarkable
Der Wasserversuch als Nierenfunktionsprüfung. Eine Zusammenfassung für den Kliniker und praktischen Arzt.. Arch Intern Med (Chic). 1932;49(6):1099. doi:10.1001/archinte.1932.00150130222023