Lymphosarcoma and lymphatic leukemia have been regarded as two distinct pathologic conditions. In recent years, however, the leukemic state has come to be regarded as merely a phase of circulating metastases from lymphosarcoma. This implies that all patients with leukemia present the condition of lymphosarcoma earlier in their histories, and that this condition may not have been clinically evident because of the deep location of the involved lymph nodes.
A review of the entire literature for the presentation of evidence proving the correctness of the hypothesis stated is beyond the scope of this report. However, attention may be called to the more recent reports which deal with cases similar to the ones we present.
Evans and Leucutia,1 in 1926, treated sixteen patients who had lymphosarcoma with deep roentgen therapy; all showed a uniformly rapid subsidence of symptoms. The exact dosage employed in these cases is not stated by the
KATO K, BRUNSCHWIG A. ACUTE LEUKEMIA FOLLOWING LYMPHOSARCOMA. Arch Intern Med (Chic). 1933;51(1):77-89. doi:10.1001/archinte.1933.00150200080007