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August 1933


Author Affiliations


From the Medical Service of Dr. J. N. Cohen and the Laboratories of the Greenpoint Hospital.

Arch Intern Med (Chic). 1933;52(2):317-324. doi:10.1001/archinte.1933.00160020155006

A recent paper by Scott and Zweighaft1 has again raised a longstanding controversy on the question of the absorption of dextrose by rectum. They have demonstrated in a series of studies on fifty medical students that there is no evidence of the absorption of dextrose when it is given in a 10 per cent concentration (40 Gm.). The literature disclosed a marked difference of opinion regarding the absorbability of dextrose administered by this route. In view of the therapeutic importance of the answer to this question, the authors have attempted an investigation of this problem in an unselected series of diabetic and nondiabetic patients in a hospital ward.

The following investigators found evidence that dextrose is absorbed when it is instilled into the rectum. Schoenborn2 showed that there was a maximum absorption of dextrose in from one to two hours. Von Leube3 found 63 out of 70

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