September 1933


Author Affiliations


From the Department of Pathology, Cook County Hospital (R. H. Jaffé, Director) and the departments of medicine, Cook County Hospital and Northwestern University Medical School.

Arch Intern Med (Chic). 1933;52(3):429-446. doi:10.1001/archinte.1933.00160030090007

This study was undertaken to determine relative ventricular weights in cardiovascular syphilis. Interest in the wider problem of total cardiac weights and relative proportions of the various chambers in the important etiologic types of cardiac disease stimulated this more extensive investigation.

In any presentation of this subject, mention must be made of the classic work of Muller, whose monograph was published in 1883. His work was done on unfixed hearts, and, according to Lewis,1 "the lines of the cuts are described in insufficient detail." We will not attempt a comparison of our figures with his. Lewis reported in 1913 a method of dividing and weighing the heart devised in a study of ventricular hypertrophy and preponderance. He deplored the tendency to diagnose relative hypertrophy from inspection alone and the fact that the method of weighing had not been adopted in teaching institutes and was not employed "by those who

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