Diseases of a cutaneous nature have long been associated with the ingestion of carbohydrate. The introduction of modern biochemical and micro-analytic methods has made possible the investigation of this interesting relationship. In addition the field has been enlarged, and now includes a variety of infections other than those essentially dermatologic. The problem, however, as a scientific study is complicated by the many factors involved in carbohydrate metabolism, each of which takes part in the transformations which the carbohydrate molecule undergoes in the animal body.
The first studies in this field were devoted primarily to an examination of the values for blood sugar after fasting in the more common dermatoses: acne vulgaris, seborrhea, psoriasis, sycosis, eczema, dermatitis rosacea, urticaria, etc. Earlier investigators (Schwartz, Highman and Malinkin,1 Levin and Kahn,2 McGlasson,3 Haldin-Davis and Wills4) reported hyperglycemia with fasting in most of the aforementioned conditions. The more recent studies,
SCHMIDT EG, EASTLAND JS, BURNS JH. INFECTION AND THE TOLERANCE FOR DEXTROSE. Arch Intern Med (Chic). 1934;54(3):466-481. doi:10.1001/archinte.1934.00160150153010